Skip to main content

BACTERIA SKIN COLONIZATION AND INFECTIONS IN PATIENTS WITH ECZEMA

ATTENTION:

BEFORE YOU READ THE ABSTRACT OR CHAPTER ONE OF THE PROJECT TOPIC BELOW, PLEASE READ THE INFORMATION BELOW.THANK YOU!

 

INFORMATION:

YOU CAN GET THE COMPLETE PROJECT OF THE TOPIC BELOW. THE FULL PROJECT COSTS N5,000 ONLY. THE FULL INFORMATION ON HOW TO PAY AND GET THE COMPLETE PROJECT IS AT THE BOTTOM OF THIS PAGE. OR YOU CAN CALL: 08068231953, 08168759420

 

 

BACTERIA SKIN COLONIZATION AND INFECTIONS IN PATIENTS WITH ECZEMA

 

CHAPTER ONE

1.1 Background of the study

Relationship between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-Allergen-specific Antibodies in Sera of Children with Atopic Eczema/Dermatitis

Syndrome

In this study we investigated skin bacterial colonization,

allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2 – 17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children).

1.2 Statement of the problem

The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization.

The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence

of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema dermatitis syndrome. Key words: antiphospholipid antibody; inhalant allergens; bacterial colonization; Staphylococcus aureus. (Accepted June 26, 2003.)

Atopic eczema/dermatitis syndrome (AEDS) (1) is a chronic cutaneous inflammatory disease that nearly always begins in childhood and follows a remitting/ flaring course that continues throughout life (2 – 4). An

eczematous, severely pruritic disease, AEDS may be

exacerbated by several triggering factors, e.g. allergens,

irritants, seasonal/climate changes and psychic stress.

The disease often moderates with age, but patients

suffer from a life-long skin sensitivity to irritants.

Atopy predisposes patients to various occupational skin

diseases. Most, but not all, individuals with AEDS have

a personal or family history of allergic rhinitis or

asthma (5), along with increased serum IgE antibodies

against inhalant or food allergens (extrinsic type) (6, 7),

or against epithelial antigens (8, 9). The role of IgE

remains obscure, however. The skin bacterial colonization

(as a base of superantigens) and the exogenous

allergens play an important role in the progression of

the clinical status. Antinuclear (ANA) antibodies have

also been observed in an animal model of atopic

dermatitis (10). In addition, the impaired skin barrier,

sweating function (11) and ion content (12) can

contribute to the pathogenesis of AEDS, including

IgE-mediated hypersensitivity against sweat antigen

(13) or epithelial antigens (9). For a better understanding

of the antibody pattern in AEDS (14), we

compared the occurrence of allergen-specific IgE and

antiphospholipid (APL) antibodies, including anticardiolipin

(ACL), and anti-b2-glucoprotein I (Ab2GPI),

as well as ANA antibodies in 72 children with AEDS

from the aspect of bacterial colonization.

1.3 Patients and methods

Seventy-two children (34 boys, 38 girls; mean age 8 years,

range 2 – 17) with atopic eczema/dermatitis syndrome were

included in the study; all were suffering from serious or

medium – severe forms of the disease. The average SCORAD

index (15) was 48.3 (range 24 – 90). The control group

comprised 22 healthy children (10 boys, 12 girls; mean age

8.6 years, range 1.5 – 14). A tampon was used to take samples

from the affected skin for microbiological examination, and

the bacteria were isolated on blood agar medium. The number

of bacteria was determined using a semiquantitative method.

The detection of ANA antibodies was carried out by indirect

immunofluorescence on HEp2 cells. ELISA assays were used

for measuring anticardiolipin and anti-b2-glycoprotein I (16).

Serum total IgE was detected by laser nephelometry. The

allergen-specific IgE was determined by an immunoblot assay

(INTEX Basel). Statistical analysis was performed using

Fisher’s exact test and unpaired t-test and the odds ratio was

calculated.

HOW TO GET THE FULL PROJECT WORK

 

PLEASE, print the following instructions and information if you will like to order/buy our complete written material(s).

 

HOW TO RECEIVE PROJECT MATERIAL(S)

After paying the appropriate amount (#5,000) into our bank Account below, send the following information to

08068231953 or 08168759420

 

(1)    Your project topics      

(2)     Email Address

(3)     Payment Name

(4)    Teller Number

We will send your material(s) after we receive bank alert

 

BANK ACCOUNTS

Account Name: AMUTAH DANIEL CHUKWUDI

Account Number: 0046579864

Bank: GTBank.

 

OR

Account Name: AMUTAH DANIEL CHUKWUDI

Account Number: 2023350498

Bank: UBA.

 

 

 

FOR MORE INFORMATION, CALL:

08068231953 or 08168759420

 

 

AFFILIATE LINKS:

myeasyproject.com.ng

easyprojectmaterials.com

easyprojectmaterials.net.ng

easyprojectsmaterials.net.ng

easyprojectsmaterial.net.ng

easyprojectmaterial.net.ng

projectmaterials.com.ng

googleprojectsng.blogspot.com

myprojectsng.blogspot.com.ng

https://projectmaterialsng.blogspot.com.ng/

https://foreasyprojectmaterials.blogspot.com.ng/

https://mypostumes.blogspot.com.ng/

https://myeasymaterials.blogspot.com.ng/

https://eazyprojectsmaterial.blogspot.com.ng/

https://easzprojectmaterial.blogspot.com.ng/

 

 


Comments

Popular posts from this blog

THE FACTORS RESPONSIBLE FOR PUPILS LATENESS TO SCHOOL IN PRIMARY SCHOOL

ATTENTION: BEFORE YOU READ THE PROJECT WORK, PLEASE READ THE INFORMATION BELOW. THANK YOU! TO GET THE FULL PROJECT FOR THE TOPIC BELOW PLEASE CALL: 08168759420, 08068231953 TO GET MORE PROJECT TOPICS IN YOUR DEPARTMENT, PLEASE VISIT: www.easyprojectmaterials.com www.easyprojectsolutions.com www.worldofnolimit.com THE FACTORS RESPONSIBLE FOR PUPILS LATENESS TO SCHOOL IN PRIMARY SCHOOL ABSTRACT This study was designed to find out those factors that are responsible for pupils lateness to school in Agabi primary school in Orhionmwon Local Government Area of Delta State. The incessant occurrence of chart and some time criminal behaviour not only by the audit population, but also the students of this country in recent times has since began to give cause of concern, particularly to parents, government and school administrators. Questionnaires from a sample of four

ADVERTISING AS A ‘’POWER TOOL’’ FOR BUSINESS GROWTH (A CASE STUDY OF NIGERIAN BOTTLING COMPANY PLC)

ATTENTION: BEFORE YOU READ THE PROJECT WORK, PLEASE READ THE INFORMATION BELOW. THANK YOU! TO GET THE FULL PROJECT FOR THE TOPIC BELOW PLEASE CALL: 08168759420, 08068231953 TO GET MORE PROJECT TOPICS IN YOUR DEPARTMENT, PLEASE VISIT: www.easyprojectmaterials.com www.easyprojectsolutions.com www.worldofnolimit.com ADVERTISING AS A ‘’POWER TOOL’’ FOR BUSINESS GROWTH (A CASE STUDY OF NIGERIAN BOTTLING COMPANY PLC) ABSTRACT The study was on Advertising as a Power Tool for Business Growth. Advertising refers to any form of non-personal presentation or promotion of ideas, goods and services by an identified sponsor. The raison d’ taire of advertising is to create awareness of a product and to further stimulate brand preference. Therefore, its role in the pursuant of a company’s profit making objective cannot be over emphasized. The study used the Nigerian Bottling Co

AFRICAN STANDBY FORCE: PROSPECTS FOR REGIONAL SECURITY

  ATTENTION: BEFORE YOU READ THE ABSTRACT OR CHAPTER ONE OF THE PROJECT TOPIC BELOW, PLEASE READ THE INFORMATION BELOW.THANK YOU!   INFORMATION: YOU CAN GET THE COMPLETE PROJECT OF THE TOPIC BELOW. THE FULL PROJECT COSTS N5,000 ONLY. THE FULL INFORMATION ON HOW TO PAY AND GET THE COMPLETE PROJECT IS AT THE BOTTOM OF THIS PAGE. OR YOU CAN CALL: 08068231953, 08168759420       AFRICAN STANDBY FORCE: PROSPECTS FOR REGIONAL SECURITY   TABLE OF CONTENTS CONTENTS                                                        PAGE(S) TITLE PAGE………………………………………………………………   i APPROVAL PAGE………………………………….……………………   ii DECLARATION…………………………………………………….……   iii DEDICATION……………………….……………………………………   iv ACKNOWLEDGEMENT………….………………………….…………   v TABLE OF CONTENTS………………………………………………… vi-ix LIST OF TABLES ……………………………………………………….   x LIST OF FIGURES ……………………………………………………… xi LIST OF ABBREVIATIONS…….……………………………………… xii-xiii ABSTRACT………………………………………………………………… xiv-xv   CHAPTER